Source of Support: None, Conflict of Interest: None
Pulmonary surfactant, a soap-like substance, which has been shown to line the alveoli of the lung is responsible for the stable co-existence of alveoli of varied sizes. It has the unique capacity to change surface tension with area. Inactivation or depletion of surfactant material leads to various pulmonary disorders. In this overview, the important role of surfactant in mechanics of breathing, methods of assessment of surfactant activity and the factors affecting the lung surfactant properties are discussed.