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Lung India Official publication of Indian Chest Society  
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Year : 1986  |  Volume : 4  |  Issue : 1  |  Page : 29-33

Aspergillus Specific IgE Estimation By Radioallergosorbent Techniqe (Rast) In Obstructive Airways Disease At Agra



Correspondence Address:
S. K Sharma


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Source of Support: None, Conflict of Interest: None


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The radioallergosorbent technique (RAST) was used to measure the levels of Aspergillus specific IgE in 25 normal controls, 25 cases of extrinsic bronchial asthma and 25 cases of allergic broncho-pulmonary aspergillosis with a view to study the clinical role and its correlation with sputum culture, skin sensitivity and severity of airways obstruction. The test was performed using Pharmacia diagnostic kits with antigen derived from Aspergillus fumigatus. Abnormal levels of Aspergillus specific IgE were observed in 84% cases of bronchial asthma but none of the controls. 86.7% of all cases with positive skin test had positive radioallergosorbent test and there was no false positive reaction. There was a positive correlation of Aspergillus specific IgE with skin test positivity and with FEV1 / FVC%.


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