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Lung India Official publication of Indian Chest Society  
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Year : 1990  |  Volume : 8  |  Issue : 1  |  Page : 11-14

A Comparative Clinical Trial Of Aerosol Budesonide And Oral Prednisolone In Patients Of Bronchial Asthma



Correspondence Address:
K. R Sethuraman


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The aerosol budesonide was compared with oral prednisolone for its efficacy, tolerability and adrenal suppression. Twenty-eight patients, randomly divided into two groups of 14 patients each, participated in the trial. The study revealed that aerosol budesonide (200 mg twice daily) was significantly more effective than oral prednisolone (0.5 mg/kg body weight) as measured by peak expiratory flow rates (PEFR) and by symptom scores. Further, aerosol budesonide did not produce any hypothalamic – pituitary – adrenal axis suppression while oral prednisolone did.


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