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Lung India Official publication of Indian Chest Society  
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Year : 1991  |  Volume : 9  |  Issue : 2  |  Page : 49-51

Bronchoalveolar Lavage Cells In Bronchial Asthma



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J. P Rishi


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Broncho Alveolar Lavage Fluid (BALF) from 30 asthmatics and 20 age and sex matched controls was analysed for fluid recovery, TLC, DLC and mast cells. In asthmatics, fluid recovery was significantly decreased (p < 0.05) TLC was similar to that of controls and DLC revealed a significant increase in eosinophils (p < 0.05) and a slight decrease in macrophages. Mast Cells were significantly increased in asthmatics (p < 0.05). BALF eosinophilia, as seen in asthmatics, is a primary inflammatory event of the airways and not secondary to peripheral blood eosinophilia. Besides, peripheral blood eosinophilia was not a constant finding in all asthmatics. BALF eosinophils increased with increasing severity of asthma (FEV1) and similarly mast cells also Increased with increasing severity of the disease. Out of the two, mast cells correlated better with the severity.


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