Source of Support: None, Conflict of Interest: None
Alternate day short course regimens were compared with daily short courses consisting of lsniazid (H), ethambutol (E), rifampicin (R) and pyrazinamide (Z). Drug toxicity was equally frequent in both. Nature and severity of toxicity varied between the two groups. Alternate day regimen does not appear to confer advantages over daily regimens in the field.