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Lung India Official publication of Indian Chest Society  
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Year : 1993  |  Volume : 11  |  Issue : 4  |  Page : 157-162

Evaluation Of Serum And Pleural Fluid Immune Complexes Level In Tubercular And Non-Tubercular Pleural Effusions

Correspondence Address:
K. B Gupta

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Source of Support: None, Conflict of Interest: None

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Circulating Immune Complexes (CIC) were detected in serum and pleural fluid by polyethylene glycol (PEG) precipitation method in 40 freshly diagnosed cases of pleural effusion (20 tubercular pleural effusion and 20 non-tubercular pleural effusion). Serum levels of CIC were also detected in twenty healthy persons (control). The mean levels of CIC in tubercular and non-tubercular pleural effusion were found to be significantly higher as compared to healthy control in serum i.e. 229.35 ± 69.47 and 391.5 ± 94.77 in serum, 155.5 ± 65.21 and 191.75 ± 58.33 in pleural fluid of tubercular and non-tubercular group respectively as compared to serum CIC in control 97.85 ± 62.58. It may be concluded that CIC may play an important role and are involved in the pathogenesis of exudative pleural effusion i.e. in tubercular and malignant pleural effusion.

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