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Lung India Official publication of Indian Chest Society  
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Year : 1998  |  Volume : 16  |  Issue : 1  |  Page : 14-16

Protein Bound Carbohydrates As Diagnostic Tools In Pleural Effusion Of Bronchogenic Carcinoma Patients



Correspondence Address:
A. J Vanisree


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Source of Support: None, Conflict of Interest: None


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Sialic acid, hexose, hexosamine, and fucose were estimated in pleural effusions of 60 lung cancer patients to establish their significance as markers of lung malignant pleural effusions. Pleural effusions of lung cancer patients exhibited significantly higher levels of sialic acid(12.9±1.7 mg/dl vs 10.5±0.5 mg/dl, p<0.001), hexose(8.2±0.9 mg/dl vs 7.8±0.8 mg/dl, p<0.01), hexosamine(11.1±1.5 mg/dl vs 9.6±0.5 mg/dl, p<0.001) and fucose (8.1±0.7 mg/dl vs 7.7±0.3 mg/dl, P<0.001) compared to the non-malignant pleural effusions. It is there suggested that these findings may have clinical implications and help in the diagnosis of pleural effusions associated with lung malignancy.


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