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Lung India Official publication of Indian Chest Society  
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Year : 2000  |  Volume : 18  |  Issue : 3  |  Page : 77-80

Acute Organophosphate Compound And Carbamate Poisoning : A Study Of 36 Cases In The Intensive Respirtory Care Unit



Correspondence Address:
P. N Chhajed


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Source of Support: None, Conflict of Interest: None


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A retrospective study of organophosphate and carbamate poisoning, its management and outcome in 36 patients admitted in intensive respiratory care unit (IRCU) over a period of one year was carried out in an urban tertiary care hospital. The mortality was 11.11% and there was no significant correlation with the type of poison consumed. Proximal muscle weakness, neck muscle weakness and weak gag reflex are good clinical indicators to predict the possibility of requiring ventilator support. Majority of the intubated patients in organophosphate and carbamate compound poisoning will require artificial ventilation. 5 patients (9.09%) developed intermediate syndrome and all patients recovered. Tracheostomy was done in 68% patients for prolonged ventilator support. Aspiration pneumonia, low pH values (= or < 7.012) and arterial PCO2 levels (= or > 79.9 mm Hg) at presentation were significant factors associated with mortality.


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