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Clinically an unusual case of spontaneous rupture of oesophagus into right pleural cavity resulting in hydropneumothorax following radiotherapy for squamous cell carcinoma of oesophagus is reported. The oesophagopleural fistula was suspected because of swallowed fluid appearing in pleural space and draining though the chest tube. The diagnosis was confirmed by barium swallow study. The classical signs and symptoms of spontaneous rupture of oesophagus were absent.