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We present a case of sclerosing mesenteritis, probably of tuberculosis etiology in a 45 years old male patient where the diagnosis was made on post-mortem examination. Sclerosing mesenteritis is a rare, idiopathic and benign mesenteric lesion characterized by fat necrosis, fibrosis and chronic inflammation seen in men in middle or late life. In some cases it may have an aggressive outcome. Though the etiological reasons have been varied, association of sclerosing mesenteritis with tuberculosis has not been reported previously.