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Lung India Official publication of Indian Chest Society  
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Year : 2006  |  Volume : 23  |  Issue : 4  |  Page : 151-153

A rare case of primary mediastinal non-seminomatous germ cell carcinoma in a 18 year old boy

Department of TB & Respiratory Disease, Calcutta National Medical College & Hospital, Kolkata., India

Correspondence Address:
S Kundu
Department of Chest Medicine, Midnapore Medical College, Distt. Pascim Medinapur, West Bengal.
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0970-2113.44389

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A 18 year old Hindu boy presented with left sided chest pain, shortness of breath, high fever and swelling of left side of chest and left arm. He was anaemic with fea­tures of Superior Venacaval (SVC) Obstruction. CT Scan of Thorax revealed huge heterogeneous anterior mediastinal mass. He had very high level of serum alpha fetoprotein. CT guided Fine Needle Aspiration Cytology (FNAC) gives the diagno­sis of Yolk sac tumour . As USG of abdomen and testes were normal, it is a case of primary mediastinal Yolk sac ( Endodermal sinus ) tumour. Although nonseminomatous germ cell tumour is 30-40% more common in Klinefelter's syndrome [1] , Karyotyping of this patient was normal.

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