Home | About us | Editorial Board | Search | Ahead of print | Current Issue | Archives | Instructions | Online submissionContact Us   |  Subscribe   |  Advertise   |  Login  Page layout
Wide layoutNarrow layoutFull screen layout
Lung India Official publication of Indian Chest Society  
  Users Online: 570   Home Print this page  Email this page Small font size Default font size Increase font size
CASE REPORT
Year : 2008  |  Volume : 25  |  Issue : 4  |  Page : 155-157

Endogenous excess cortisol production and diabetes mellitus as predisposing factors for pulmonary cryptococcosis: A case report and literature review


Department of Pulmonary Medicine and Pathology, Christian Medical College, Vellore, Tamil Nadu, India

Correspondence Address:
B Thangakunam
Dept. of Pulmonary Medicine, Christian Medical College, Vellore 632004, Tamil Nadu
India
Login to access the Email id

Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0970-2113.45281

Rights and Permissions

Pulmonary cryptococcosis usually occurs as an opportunistic infection in immuno­compromised patients. Endogenous Cushing's syndrome is associated with cortisol excess and can predispose to development of cryptococcal infections. We report a case of diabetic patient with ACTH secreting pituitary tumour who developed a cavitating lung mass. Computed tomography-guided biopsy of the lesion revealed mucicarminophilic budding forms of cryptococcus. Broncheoalveolar lavage culture grew Cryptococcus neoformans. There was radiological response to treatment with liposomal Amphotericin, but patient ultimately succumbed to septicemia and multiorgan failure. Opportunistic infections with organisms like Cryptococcus neoformans, should be considered in patients with en­dogenous Cushing's syndrome and a pulmonary infiltrate.


[FULL TEXT] [PDF]*
Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed1957    
    Printed72    
    Emailed1    
    PDF Downloaded344    
    Comments [Add]    

Recommend this journal