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Lung India Official publication of Indian Chest Society  
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Year : 2010  |  Volume : 27  |  Issue : 1  |  Page : 33-36

Whole lung lavage for pulmonary alveolar proteinosis

1 Department of Respiratory Medicine, Apollo Hospitals, Chennai - 600 006, India
2 Santosham Chest Hospital, Chennai, India
3 Department of Cardiothoracic Surgery, Apollo Hospitals, Chennai - 600 006, India

Correspondence Address:
R Narasimhan
Department of Respiratory Medicine, Apollo Hospitals, Greams Road, Chennai - 600 006
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0970-2113.59267

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A 26-year-old male presented with complaints of dry cough of six months and progressive breathlessness of three months duration. He was coughing out milky white sputum for two months and had lost 12 kg weight in two months. He had an evening rise in temperature of one month duration. Clinically, the patient was in respiratory distress and the respiratory system examination revealed bilateral velcro crackles. High resolution computed tomography chest showed bilateral diffuse reticulonodular opacities and "Crazy Paving" pattern suggestive of alveolar proteinosis. Broncho alveolar lavage showed eosinophilic granular material, which was periodic acid-Schiff positive. Open lung biopsy was done to confirm the diagnosis and the histopathologic examination revealed eosinophilic secretions with granular appearance suggestive of pulmonary alveolar proteinosis. Subsequently, patient underwent bilateral sequential whole lung lavage under general anesthesia. Patient showed marked clinical and radiological improvement after sequential whole lung lavage.

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