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Lung India Official publication of Indian Chest Society  
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Year : 2011  |  Volume : 28  |  Issue : 3  |  Page : 201-204

Diffuse interstitial lung infiltrates in a smoker with human immunodeficiency virus infection

1 Department of Internal Medicine, The Brooklyn Hospital Center, New York, USA
2 Department of Pulmonary Medicine, The Brooklyn Hospital Center, New York, USA

Correspondence Address:
Praveen K Jinnur
Department of Pulmonary Medicine, 121 Dekalb Ave, Brooklyn, NY-11201
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0970-2113.83978

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Pulmonary Langerhans cell histiocytosis is a rare interstitial lung disease characteristically affecting middle-aged smokers. It has unpredictable clinical course and may be associated with malignant neoplasms. Opportunistic lung infections are frequently considered when patients with Human immunodeficiency virus (HIV) infection present with respiratory symptoms and an abnormal chest X-ray. Though fiberoptic bronchoscopy with bronchoalveolar lavage is diagnostic for infectious etiologies, surgical lung biopsies are preferred to diagnose noninfectious lung diseases and to help guide appropriate therapy. In the present study, we report a case of progressive bilateral lung infiltrates in a smoker with HIV infection which presented a diagnostic dilemma in view of coexistent HIV infection. Analysis of clinical symptomatology aided by surgical lung biopsy helped in diagnosis.

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