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Lung India Official publication of Indian Chest Society  
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REVIEW ARTICLE
Year : 2020  |  Volume : 37  |  Issue : 5  |  Page : 421-424

Respiratory infections: Role of Vitamin D and surfactant proteins A and D


Department of Pediatrics, JIPMER, Puducherry, India

Correspondence Address:
Dr. Niranjan Biswal
Department of Pediatrics, JIPMER, Puducherry - 605 006
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/lungindia.lungindia_369_18

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Respiratory tract infection is the common viral infection and the principal cause of death among children under 5 years of age. It damages lung epithelium and increases mucus production and inflammation, leading to dyspnea. The sunshine vitamin (Vitamin D) and surfactant protein (SP) A and D along with their usual function play an important role in host defense. This article reviews with immune role of Vitamin D and SP A and D which aids excessive cytokines production, boosts phagocytosis, hinders inflammatory activity, and thus acts as a first-line defense against lung pathogens.


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