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Lung India Official publication of Indian Chest Society  
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Year : 1989  |  Volume : 7  |  Issue : 2  |  Page : 79-83

A Study Of Short - Course Chemotherapy For Pulmonary Tuberculosis Under Programme (Field) Conditions In Pondicherry


Correspondence Address:
V. K Padmanabhan


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Source of Support: None, Conflict of Interest: None


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A short-course regimen has been implemented in Pondicherry with the objective of obtaining information on its feasibility, acceptability, toxicity and efficacy under programme (field) conditions. A total of 1441 patients received a six month period short-course regimen of lsoniazid (300 mg), Rifampicin (450 mg) and Pyrazinamide (1.5 g) daily for two months initially followed by Rifampicin (600 mg) and lsoniazid (600 mg) twice a week for the next four months. Ninety-eight percent of the patients had either mild or moderate disease radiologically. Chemotherapy was completed by 68% of the patients. One of the patients had smear positivity at the end of chemotherapy; 81% showed radiographic improvement. Successful short-course chemotherapy is feasible under existing programme conditions


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