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Lung India Official publication of Indian Chest Society  
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Year : 1990  |  Volume : 8  |  Issue : 3  |  Page : 129-132

Small Airways Dysfunction In Cotton Dust Exposed Workers

Correspondence Address:
H Venkatakrishna-Bhatt

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Source of Support: None, Conflict of Interest: None

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Exposure to cotton dust produces acute changes In FEV1 over a shift and chronic changes as evidenced by loss of percentage of predicted value. In this report pre- and post- shift difference in FEF25-75% value and percentage of predicted FEF25-75% in control and exposed workers (non-byssinotics and byssinotics) were evaluated and related to blood histamine levels. The results revealed that the percentage of predicted FEF25-75% showed higher reduction in byssinotics than non-byssinotics and acute changes in FEF25-75% also showed greater decline in byssinotics, than non-byssinotics. This study suggests that FEF25-75% is an early Indicator of airway (small airway) obstruction in byssinotics.

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