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Lung India Official publication of Indian Chest Society  
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Year : 1990  |  Volume : 8  |  Issue : 3  |  Page : 153-155

Bronchogenic Carcinoma - Optimal Number Of Biopsy Specimens Required For Diagnosis



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S. K Sarkar


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The purpose of this study was to determine the optimal number of biopsy specimens required to diagnose the endoscopically visible bronchogenic carcinoma, using fiberoptic bronchoscope. Twenty six patients were Included In the study, three biopsy specimens were taken from each growth, and subjected for histopathoiogical examination. Eight out of 78 biopsy samples were negative for growth and all the tumors could be diagnosed with in the first two biopsy samples. The estimated probability of diagnosis after one biopsy was 0.8974, after two biopsies 0.9894 and after three It was 0.9989. Our experience suggests that two biopsy samples are good enough to diagnose a case of bronchogenic carcinoma and the complications related with the prolonged procedure and risk of bleeding can be reduced.


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