Source of Support: None, Conflict of Interest: None
Study of serial peak expiratory flow rate (PEFR) changes in 30 patients of bronchial asthma showed maximum improvement following oral administration of the drug at four hours, while maximum improvement following inhalational and intravenous route occurred at 90 minutes. On inter group comparison, inhalational and intravenous routes were found to be superior to oral route upto 90 minutes, but at four hours the differences were statistically non-significant in inhalational group. When the intervals. A high incidence of side effects was observed with intravenous salbutamol while inhalational route was remarkably free from side effects. Inhalational route of salbutamol is recommended for long term management of stable bronchial asthma.