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Most of the chronic pulmonary tuberculosis patients usually take asylum Tuberculosis Hospitals as the last resort to have their lungs sterllised from M. tuberculosis. Govt.Hospital of Thoracic Medicine, Tambaram, Madras, offers its vast experienced in the management of pulmonary tuberculosis patients with recurring treatment failures. Medical salvage in those patients is essentially restricted to prevent any further progression of the disease and to sterllise the damaged lungs from drug resistant tubercle bacilli. Salvage medication is planned scientifically to meet the requirements of each patient. 87% patients had sputum conversion at the end of six months chemotherapy. All the 100 patients remained culture negative for M. tuberculosis after nine months of treatment.