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Lung India Official publication of Indian Chest Society  
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Year : 1991  |  Volume : 9  |  Issue : 1  |  Page : 22-24

Role Of Sputum Beta Lactamases In The Pathogenesis Of Bronchopulmonary Infections

Correspondence Address:
Thangam Menon

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Source of Support: None, Conflict of Interest: None

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Beta lactamase activity was measured in sputum samples from patients with bronchopulmonary infections. Of the 44 sputum samples screened, 26 were postive for Beta lactamase by the quantitative assay. Aerobic cultures of the 26 positive samples organisms such as Klebslella (nine), Staphylococcus auresus (six), Pseudomonas aeruginosa (two), Streptococcus pyogenes (four) Nelsseria spp. (nine) Candida spp. (eight) and Streptococcus viridans (one) among which only 17 strains of pathogenic bacteria were found to produced b lactamase. Hence sources of sputum b lactamase may be bacteria which are not considered to be conventionally pathogenic and they may contribute to the disease process by the mechanism of “indirect pathogenicity”.

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