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Lung India Official publication of Indian Chest Society  
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Year : 2021  |  Volume : 38  |  Issue : 7  |  Page : 61-63

Fibrotic interstitial lung disease occurring as sequelae of COVID-19 pneumonia despite concomitant steroids

1 P.D. Hinduja Hospital and Medical Research Centre, Mumbai, Maharashtra, India
2 Department of Internal Medicine, Breach Candy Hospital Trust, Mumbai, Maharashtra, India
3 Department of Pulmonary Medicine, P.D. Hinduja Hospital and Medical Research Centre, Mumbai, Maharashtra, India
4 Department of Radio Diagnosis, Breach Candy Hospital Trust, Mumbai, Maharashtra, India

Correspondence Address:
Dr. Zarir Farokh Udwadia
4, P.D. Hinduja Hospital and Research Centre, Veer Savarkar Marg, Mumbai - 400 016, Maharashtra
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/lungindia.lungindia_533_20

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A 75-year-old female with no history of lung disease developed severe pulmonary fibrosis within 1 month of acute severe COVID-19 pneumonia. She developed dry basal crackles, hypoxia needing home oxygen, and computed tomography changes which dramatically evolved from acute ground-glass opacities to honeycombing and traction bronchiectasis. Interestingly, these changes occurred despite her being on steroids through most of her hospital stay. She is being commenced on pirfenidone and her responses are carefully monitored, but the role of antifibrotic drugs are unclear and will only be established from large clinical trials.

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